E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts

E2F-2 is a retinoblastoma (Rb)-regulated transcription factor induced during terminal erythroid maturation. Cyclin E-mediated Rb hyperphosphorylation induces E2F transcriptional activator functions. We previously reported that deregulated cyclin E activity causes defective terminal maturation of nuc...

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Udgivet i:Mol Cell Biol
Main Authors: Swartz, Kelsey L., Wood, Scott N., Murthy, Tushar, Ramirez, Oscar, Qin, Gangjian, Pillai, Manoj M., Rao, Sridhar, Minella, Alex C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192079/
https://ncbi.nlm.nih.gov/pubmed/27795297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00274-16
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