Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts

BACKGROUND: During the final stages of differentiation of mammalian erythroid cells, the chromatin is condensed and enucleated. We previously reported that Rac GTPases and their downstream target, mammalian homolog of Drosophila diaphanous 2 (mDia2), are required for enucleation of in vitro cultured...

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Autores principales: Ji, Peng, Yeh, Victor, Ramirez, Tzutzuy, Murata-Hori, Maki, Lodish, Harvey F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995558/
https://ncbi.nlm.nih.gov/pubmed/20823130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.029827
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