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Mammalian erythroblast enucleation requires PI3K-dependent cell polarization

Enucleation, the final step in terminal differentiation of mammalian red blood cells, is an essential process in which the nucleus surrounded by the plasma membrane is budded off from the erythroblast to form a reticulocyte. Most molecular events in enucleation remain unclear. Here we show that enuc...

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Detalhes bibliográficos
Main Authors: Wang, Junxia, Ramirez, Tzutzuy, Ji, Peng, Jayapal, Senthil Raja, Lodish, Harvey F., Murata-Hori, Maki
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283871/
https://ncbi.nlm.nih.gov/pubmed/22331356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.088286
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