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Mammalian erythroblast enucleation requires PI3K-dependent cell polarization

Enucleation, the final step in terminal differentiation of mammalian red blood cells, is an essential process in which the nucleus surrounded by the plasma membrane is budded off from the erythroblast to form a reticulocyte. Most molecular events in enucleation remain unclear. Here we show that enuc...

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Main Authors: Wang, Junxia, Ramirez, Tzutzuy, Ji, Peng, Jayapal, Senthil Raja, Lodish, Harvey F., Murata-Hori, Maki
格式: Artigo
語言:Inglês
出版: Company of Biologists 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283871/
https://ncbi.nlm.nih.gov/pubmed/22331356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.088286
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