GM-CSF signalling blockade and chemotherapeutic agents act in concert to inhibit the function of myeloid-derived suppressor cells in vitro

Immune evasion is a recently defined hallmark of cancer, and immunotherapeutic approaches that stimulate an immune response to tumours are gaining recognition. However tumours may evade the immune response and resist immune-targeted treatment by promoting an immune-suppressive environment and stimul...

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Foilsithe in:Clin Transl Immunology
Main Authors: Gargett, Tessa, Christo, Susan N, Hercus, Timothy R, Abbas, Nazim, Singhal, Nimit, Lopez, Angel F, Brown, Michael P
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192067/
https://ncbi.nlm.nih.gov/pubmed/28090321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cti.2016.80
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