Immunogenicity and transmission reducing potency of Pfs48/45 and Pfs25 encoded by DNA vaccines administered by intramuscular electroporation

Pfs48/45 and Pfs25 are leading candidates for the development of Plasmodium falciparum transmission blocking vaccines (TBV). Expression of Pfs48/45 in the erythrocytic sexual stages and presentation to the immune system during infection in the human host also makes it ideal for natural boosting. How...

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Vydáno v:Vaccine
Hlavní autoři: Datta, Dibyadyuti, Bansal, Geetha P., Gerloff, Dietlind L., Ellefsen, Barry, Hannaman, Drew, Kumar, Nirbhay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192010/
https://ncbi.nlm.nih.gov/pubmed/27912985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.11.072
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