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Heterolytic O-O Bond Cleavage: Functional Role of Glu113 during Bis-Fe(IV) Formation in MauG

The diheme enzyme MauG utilizes H(2)O(2) to perform oxidative posttranslational modification on a protein substrate. A bis-Fe(IV) species of MauG was previously identified as a key intermediate in this reaction. Heterolytic cleavage of the O-O bond of H(2)O(2) drives the formation of the bis-Fe(IV)...

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Detalhes bibliográficos
Publicado no:J Inorg Biochem
Main Authors: Geng, Jiafeng, Huo, Lu, Liu, Aimin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191938/
https://ncbi.nlm.nih.gov/pubmed/27907864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2016.11.013
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