Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast

Chronological aging of the yeast Saccharomyces cerevisiae is attributed to multi-faceted traits especially those involving genome instability, and has been considered to be an aging model for post-mitotic cells in higher organisms. Telomeres are the physical ends of eukaryotic chromosomes, and are e...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging (Albany NY)
Main Authors: Liu, Jun, He, Ming-Hong, Peng, Jing, Duan, Yi-Min, Lu, Yi-Si, Wu, Zhenfang, Gong, Ting, Li, Hong-Tao, Zhou, Jin-Qiu
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191873/
https://ncbi.nlm.nih.gov/pubmed/27855118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101095
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