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Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast
Chronological aging of the yeast Saccharomyces cerevisiae is attributed to multi-faceted traits especially those involving genome instability, and has been considered to be an aging model for post-mitotic cells in higher organisms. Telomeres are the physical ends of eukaryotic chromosomes, and are e...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5191873/ https://ncbi.nlm.nih.gov/pubmed/27855118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101095 |
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