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Structural insights into yeast telomerase recruitment to telomeres

Telomerase maintains chromosome ends from humans to yeasts. Recruitment of yeast telomerase to telomeres occurs through its Ku and Est1 subunits, via independent interactions with telomerase RNA (TLC1) and telomeric proteins Sir4 and Cdc13, respectively. However, the structures of the molecules comp...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Chen, Hongwen, Xue, Jing, Churikov, Dmitri, Hass, Evan P., Shi, Shaohua, Lemon, Laramie D., Luciano, Pierre, Bertuch, Alison A., Zappulla, David C., Geli, Vincent, Wu, Jian, Lei, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839504/
https://ncbi.nlm.nih.gov/pubmed/29290466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.12.008
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