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Determination and augmentation of RNA sequence specificity of the Nova K-homology domains

The Nova onconeural antigens are implicated in the pathogenesis of paraneoplastic opsoclonus-myoclonus-ataxia (POMA). The Nova antigens are neuron-specific RNA-binding proteins harboring three repeats of the K-homology (KH) motif; they have been implicated in the regulation of alternative splicing o...

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Détails bibliographiques
Auteurs principaux: Musunuru, Kiran, Darnell, Robert B.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC519101/
https://ncbi.nlm.nih.gov/pubmed/15367696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh799
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