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Two ZBP1 KH domains facilitate β-actin mRNA localization, granule formation, and cytoskeletal attachment

Chicken embryo fibroblasts (CEFs) localize β-actin mRNA to their lamellae, a process important for the maintenance of cell polarity and motility. The localization of β-actin mRNA requires a cis localization element (zipcode) and involves zipcode binding protein 1 (ZBP1), a protein that specifically...

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Hlavní autoři: Farina, Kim L., Hüttelmaier, Stefan, Musunuru, Kiran, Darnell, Robert, Singer, Robert H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172732/
https://ncbi.nlm.nih.gov/pubmed/12507992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200206003
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