Mechanism of β-actin mRNA Recognition by ZBP1

Zipcode binding protein 1 (ZBP1) is an oncofetal RNA-binding protein that mediates the transport and local translation of β-actin mRNA by the KH3-KH4 di-domain, which is essential for neuronal development. The high-resolution structures of KH3-KH4 with their respective target sequences show that KH4...

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Publicado en:Cell Rep
Autores principales: Nicastro, Giuseppe, Candel, Adela M., Uhl, Michael, Oregioni, Alain, Hollingworth, David, Backofen, Rolf, Martin, Stephen R., Ramos, Andres
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300891/
https://ncbi.nlm.nih.gov/pubmed/28147274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.091
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