Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

Along with molecular abnormalities (mutations in JAK2, Calreticulin (CALR) and MPL genes), chronic inflammation is the major hallmark of Myelofibrosis (MF). Here, we investigated the in vitro effects of crucial factors of the inflammatory microenvironment (Interleukin (IL)-1β, Tumor Necrosis Factor...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Sollazzo, Daria, Forte, Dorian, Polverelli, Nicola, Romano, Marco, Perricone, Margherita, Rossi, Lara, Ottaviani, Emanuela, Luatti, Simona, Martinelli, Giovanni, Vianelli, Nicola, Cavo, Michele, Palandri, Francesca, Catani, Lucia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190072/
https://ncbi.nlm.nih.gov/pubmed/27304059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9949
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