Crucial factors of the inflammatory microenvironment (IL-1β/TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

Along with molecular abnormalities (mutations in JAK2, Calreticulin (CALR) and MPL genes), chronic inflammation is the major hallmark of Myelofibrosis (MF). Here, we investigated the in vitro effects of crucial factors of the inflammatory microenvironment (Interleukin (IL)-1β, Tumor Necrosis Factor...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sollazzo, Daria, Forte, Dorian, Polverelli, Nicola, Romano, Marco, Perricone, Margherita, Rossi, Lara, Ottaviani, Emanuela, Luatti, Simona, Martinelli, Giovanni, Vianelli, Nicola, Cavo, Michele, Palandri, Francesca, Catani, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190072/
https://ncbi.nlm.nih.gov/pubmed/27304059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9949
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