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The relevance of a low JAK2(V617F) allele burden in clinical practice: a monocentric study

Since low JAK2(V617F) allele burden (AB) has been detected also in healthy subjects, its clinical interpretation may be challenging in patients with chronic myeloproliferative neoplasms (MPNs). We tested 1087 subjects for JAK2(V617F) mutation on suspicion of hematological malignancy. Only 497 (45.7%...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Perricone, Margherita, Polverelli, Nicola, Martinelli, Giovanni, Catani, Lucia, Ottaviani, Emanuela, Zuffa, Elisa, Franchini, Eugenia, Dizdari, Arbana, Forte, Dorian, Sabattini, Elena, Cavo, Michele, Vianelli, Nicola, Palandri, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514906/
https://ncbi.nlm.nih.gov/pubmed/28422729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16744
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