Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

The secretion of soluble pro-angiogenic factors by tumor cells and stromal cells in the perivascular niche promotes the aggressive angiogenesis that is typical of glioblastoma (GBM). Here, we show that angiogenesis also can be promoted by a direct interaction between brain tumor cells, including tum...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Burgett, Monica E., Lathia, Justin D., Roth, Patrick, Nowacki, Amy S., Galileo, Deni S., Pugacheva, Elena, Huang, Ping, Vasanji, Amit, Li, Meizhang, Byzova, Tatiana, Mikkelsen, Tom, Bao, Shideng, Rich, Jeremy N., Weller, Michael, Gladson, Candece L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190064/
https://ncbi.nlm.nih.gov/pubmed/27270311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9700
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