Combination of radiotherapy and vaccination overcomes checkpoint blockade resistance

The majority of cancer patients respond poorly to either vaccine or checkpoint blockade, and even to the combination of both. They are often resistant to high doses of radiation therapy as well. We examined prognostic markers of immune cell infiltration in pancreatic cancer. Patients with low CD8(+)...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Zheng, Wenxin, Skowron, Kinga B., Namm, Jukes P., Burnette, Byron, Fernandez, Christian, Arina, Ainhoa, Liang, Hua, Spiotto, Michael T., Posner, Mitchell C., Fu, Yang-Xin, Weichselbaum, Ralph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190006/
https://ncbi.nlm.nih.gov/pubmed/27343548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9915
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