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The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications

By inducing DNA damage, radiotherapy both reduces tumor burden and enhances anti-tumor immunity. Here, we will review the mechanisms by which radiation induces anti-tumor immune responses that can be augmented using immunotherapies to facilitate tumor regression. Radiotherapy increases inflammation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Immunol
Hauptverfasser: Spiotto, Michael, Fu, Yang-Xin, Weichselbaum, Ralph R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171206/
https://ncbi.nlm.nih.gov/pubmed/28018989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aag1266
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