Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy

Checkpoint blockade immunotherapy enhances systemic antitumor immune response by targeting T cell inhibitory pathways; however, inadequate T cell infiltration has limited its anticancer efficacy. Radiotherapy (RT) has local immunomodulatory effects that can alter the microenvironment of irradiated t...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Ni, Kaiyuan, Lan, Guangxu, Chan, Christina, Quigley, Bryan, Lu, Kuangda, Aung, Theint, Guo, Nining, La Riviere, Patrick, Weichselbaum, Ralph R., Lin, Wenbin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003951/
https://ncbi.nlm.nih.gov/pubmed/29907739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04703-w
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