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Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway
The mTOR complex I (mTORC1) signaling pathway controls many metabolic processes and is regulated by amino acid signals, especially arginine. CASTOR1 has been identified as the cytosolic arginine sensor for the mTORC1 pathway, but the molecular mechanism of how it senses arginine is elusive. Here, by...
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| Publicado no: | Cell Discov |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5187391/ https://ncbi.nlm.nih.gov/pubmed/28066558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.51 |
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