Insulin receptor substrate 2 plays a crucial role in β cells and the hypothalamus

We previously demonstrated that insulin receptor substrate 2 (Irs2) KO mice develop diabetes associated with hepatic insulin resistance, lack of compensatory β cell hyperplasia, and leptin resistance. To more precisely determine the roles of Irs2 in β cells and the hypothalamus, we generated β cell–...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kubota, Naoto, Terauchi, Yasuo, Tobe, Kazuyuki, Yano, Wataru, Suzuki, Ryo, Ueki, Kohjiro, Takamoto, Iseki, Satoh, Hidemi, Maki, Toshiyuki, Kubota, Tetsuya, Moroi, Masao, Okada-Iwabu, Miki, Ezaki, Osamu, Nagai, Ryozo, Ueta, Yoichi, Kadowaki, Takashi, Noda, Tetsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC518663/
https://ncbi.nlm.nih.gov/pubmed/15467830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421484
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi