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Arsenic-induced Activation of the Homeodomain Interacting Protein Kinase 2 (HIPK2) to cAMP-response element binding protein (CREB) Axis

CREB (cAMP-response element binding protein) plays key transcriptional roles in cell metabolism, proliferation, and survival. Ser133 phosphorylation by protein kinase A (PKA) is a well-characterized CREB activation mechanism. HIPK2 (homeodomain interacting protein kinase 2), a nuclear serine/threoni...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Hashimoto, Kazunori, Tsuji, Yoshiaki
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5186405/
https://ncbi.nlm.nih.gov/pubmed/27884605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.11.015
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