Regulation of Genotoxic Stress Response by Homeodomain-interacting Protein Kinase 2 through Phosphorylation of Cyclic AMP Response Element-binding Protein at Serine 271

CREB (cyclic AMP response element-binding protein) is a stimulus-induced transcription factor that plays pivotal roles in cell survival and proliferation. The transactivation function of CREB is primarily regulated through Ser-133 phosphorylation by cAMP-dependent protein kinase A (PKA) and related...

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Auteurs principaux: Sakamoto, Kensuke, Huang, Bo-Wen, Iwasaki, Kenta, Hailemariam, Kiros, Ninomiya-Tsuji, Jun, Tsuji, Yoshiaki
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921112/
https://ncbi.nlm.nih.gov/pubmed/20573984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0015
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