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Hemin-Mediated Regulation of an Antioxidant-Responsive Element of the Human Ferritin H Gene and Role of Ref-1 during Erythroid Differentiation of K562 Cells

An effective utilization of intracellular iron is a prerequisite for erythroid differentiation and hemoglobinization. Ferritin, consisting of 24 subunits of H and L, plays a crucial role in iron homeostasis. Here, we have found that the H subunit of the ferritin gene is activated at the transcriptio...

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Bibliografski detalji
Glavni autori: Iwasaki, Kenta, MacKenzie, Elizabeth L., Hailemariam, Kiros, Sakamoto, Kensuke, Tsuji, Yoshiaki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430308/
https://ncbi.nlm.nih.gov/pubmed/16537925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2845-2856.2006
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