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Role of the Tumor Suppressor PTEN in Antioxidant Responsive Element-mediated Transcription and Associated Histone Modifications

Coordinated regulation of PI3-kinase (PI3K) and the tumor suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN) plays a pivotal role in various cell functions. PTEN is deficient in many cancer cells, including Jurkat human leukemia. Here, we demonstrate that the status of PTEN...

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Autors principals: Sakamoto, Kensuke, Iwasaki, Kenta, Sugiyama, Hiroyuki, Tsuji, Yoshiaki
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655256/
https://ncbi.nlm.nih.gov/pubmed/19158375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-07-0762
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