HIV-1 control by NK cells via reduced interaction between KIR2DL2 and HLA-C*12:02/C*14:03

Natural killer (NK) cells control viral infection in part through the interaction between killer cell immunoglobulin-like receptors (KIRs) and their HLA ligands. We investigated 504 ART-free Japanese patients chronically infected with HIV-1 and identified two KIR/HLA combinations, KIR2DL2/HLA-C*12:0...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lin, Zhansong, Kuroki, Kimiko, Kuse, Nozomi, Sun, Xiaoming, Akahoshi, Tomohiro, Qi, Ying, Chikata, Takayuki, Naruto, Takuya, Koyanagi, Madoka, Murakoshi, Hayato, Gatanaga, Hiroyuki, Oka, Shinichi, Carrington, Mary, Maenaka, Katsumi, Takiguchi, Masafumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5184766/
https://ncbi.nlm.nih.gov/pubmed/27880898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.075
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