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SHANK3 deficiency impairs heat hyperalgesia and TRPV1 signaling in primary sensory neurons
Abnormal pain sensitivity is commonly associated with autism spectrum disorders (ASDs) and affects the life quality of ASD individual. SHANK3 deficiency was implicated in ASD and pain dysregulation. Here we report functional expression of SHANK3 in mouse dorsal root ganglion (DRG) sensory neurons an...
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| 出版年: | Neuron |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5182147/ https://ncbi.nlm.nih.gov/pubmed/27916453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.11.007 |
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