SHANK3 deficiency impairs heat hyperalgesia and TRPV1 signaling in primary sensory neurons

Abnormal pain sensitivity is commonly associated with autism spectrum disorders (ASDs) and affects the life quality of ASD individual. SHANK3 deficiency was implicated in ASD and pain dysregulation. Here we report functional expression of SHANK3 in mouse dorsal root ganglion (DRG) sensory neurons an...

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Publicado no:Neuron
Main Authors: Han, Qingjian, Kim, Yong Ho, Wang, Xiaoming, Liu, Di, Zhang, Zhi-Jun, Bey, Alexandra L., Lay, Mark, Chang, Wonseok, Berta, Temugin, Zhang, Yan, Jiang, Yong-Hui, Ji, Ru-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182147/
https://ncbi.nlm.nih.gov/pubmed/27916453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.11.007
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