SHANK3 deficiency impairs heat hyperalgesia and TRPV1 signaling in primary sensory neurons

Abnormal pain sensitivity is commonly associated with autism spectrum disorders (ASDs) and affects the life quality of ASD individual. SHANK3 deficiency was implicated in ASD and pain dysregulation. Here we report functional expression of SHANK3 in mouse dorsal root ganglion (DRG) sensory neurons an...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Neuron
Päätekijät: Han, Qingjian, Kim, Yong Ho, Wang, Xiaoming, Liu, Di, Zhang, Zhi-Jun, Bey, Alexandra L., Lay, Mark, Chang, Wonseok, Berta, Temugin, Zhang, Yan, Jiang, Yong-Hui, Ji, Ru-Rong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182147/
https://ncbi.nlm.nih.gov/pubmed/27916453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.11.007
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