SHANK3 deficiency impairs heat hyperalgesia and TRPV1 signaling in primary sensory neurons

Abnormal pain sensitivity is commonly associated with autism spectrum disorders (ASDs) and affects the life quality of ASD individual. SHANK3 deficiency was implicated in ASD and pain dysregulation. Here we report functional expression of SHANK3 in mouse dorsal root ganglion (DRG) sensory neurons an...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuron
मुख्य लेखकों: Han, Qingjian, Kim, Yong Ho, Wang, Xiaoming, Liu, Di, Zhang, Zhi-Jun, Bey, Alexandra L., Lay, Mark, Chang, Wonseok, Berta, Temugin, Zhang, Yan, Jiang, Yong-Hui, Ji, Ru-Rong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182147/
https://ncbi.nlm.nih.gov/pubmed/27916453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.11.007
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