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Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes programmed chromosome breakage and massive DNA elimination to generate the somatic genome. Here, we present a complete sequence assembly of the germline genome and analyze multiple features of its structure and its rela...

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Publié dans:eLife
Auteurs principaux: Hamilton, Eileen P, Kapusta, Aurélie, Huvos, Piroska E, Bidwell, Shelby L, Zafar, Nikhat, Tang, Haibao, Hadjithomas, Michalis, Krishnakumar, Vivek, Badger, Jonathan H, Caler, Elisabet V, Russ, Carsten, Zeng, Qiandong, Fan, Lin, Levin, Joshua Z, Shea, Terrance, Young, Sarah K, Hegarty, Ryan, Daza, Riza, Gujja, Sharvari, Wortman, Jennifer R, Birren, Bruce W, Nusbaum, Chad, Thomas, Jainy, Carey, Clayton M, Pritham, Ellen J, Feschotte, Cédric, Noto, Tomoko, Mochizuki, Kazufumi, Papazyan, Romeo, Taverna, Sean D, Dear, Paul H, Cassidy-Hanley, Donna M, Xiong, Jie, Miao, Wei, Orias, Eduardo, Coyne, Robert S
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182062/
https://ncbi.nlm.nih.gov/pubmed/27892853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19090
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