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Syrosingopine sensitizes cancer cells to killing by metformin
We report that the anticancer activity of the widely used diabetic drug metformin is strongly potentiated by syrosingopine. Synthetic lethality elicited by combining the two drugs is synergistic and specific to transformed cells. This effect is unrelated to syrosingopine’s known role as an inhibitor...
में बचाया:
| में प्रकाशित: | Sci Adv |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Association for the Advancement of Science
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5182053/ https://ncbi.nlm.nih.gov/pubmed/28028542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1601756 |
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