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Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington’s Disease

The role of aggregate formation in the pathophysiology of Huntington’s disease (HD) remains uncertain. However, the temporal appearance of aggregates tends to correlate with the onset of symptoms and the numbers of neuropil aggregates correlate with the progression of clinical disease. Using highly...

詳細記述

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書誌詳細
出版年:J Huntingtons Dis
主要な著者: Osmand, Alexander P., Bichell, Terry Jo., Bowman, Aaron B., Bates, Gillian P.
フォーマット: Artigo
言語:Inglês
出版事項: IOS Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181660/
https://ncbi.nlm.nih.gov/pubmed/27886014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-160217
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