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Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) is a lethal muscle disease involving progressive loss of muscle regenerative capacity and increased fibrosis. We tested whether epigenetic silencing of the klotho gene occurs in the mdx mouse model of DMD and whether klotho silencing is an important feature of the d...
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| Publicat a: | Hum Mol Genet |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5181628/ https://ncbi.nlm.nih.gov/pubmed/27154199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw111 |
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