Arginine Metabolism by Macrophages Promotes Cardiac and Muscle Fibrosis in mdx Muscular Dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is the most common, lethal disease of childhood. One of 3500 new-born males suffers from this universally-lethal disease. Other than the use of corticosteroids, little is available to affect the relentless progress of the disease, leading many families t...

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Main Authors: Wehling-Henricks, Michelle, Jordan, Maria C., Gotoh, Tomomi, Grody, Wayne W., Roos, Kenneth P., Tidball, James G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874011/
https://ncbi.nlm.nih.gov/pubmed/20505827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010763
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