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MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex
Rett syndrome (RTT; OMIM 312750), a progressive neurological disorder, is caused by mutations in methyl-CpG-binding protein 2 (MECP2; OMIM 300005), a ubiquitously expressed factor. A genetic suppressor screen designed to identify therapeutic targets surprisingly revealed that downregulation of the c...
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| Publicado en: | Hum Mol Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5181597/ https://ncbi.nlm.nih.gov/pubmed/27288453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw156 |
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