טוען...
A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces
T-cell receptors (TCRs) have emerged as a new class of therapeutics, most prominently for cancer where they are the key components of new cellular therapies as well as soluble biologics. Many studies have generated high affinity TCRs in order to enhance sensitivity. Recent outcomes, however, have su...
שמור ב:
| הוצא לאור ב: | Protein Eng Des Sel |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5181382/ https://ncbi.nlm.nih.gov/pubmed/27624308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw050 |
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