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Role of Chaperone-Mediated Autophagy Dysfunctions in the Pathogenesis of Parkinson’s Disease

Chaperone-mediated autophagy (CMA) represents a selective form of autophagy involved in the degradation of specific soluble proteins containing a pentapeptide motif that is recognized by a cytosolic chaperone able to deliver proteins to the lysosomes for degradation. Physiologically, CMA contributes...

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Pubblicato in:Front Mol Neurosci
Autori principali: Sala, Gessica, Marinig, Daniele, Arosio, Alessandro, Ferrarese, Carlo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179559/
https://ncbi.nlm.nih.gov/pubmed/28066181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00157
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