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Co-administration of a DNA vaccine encoding the prostate specific membrane antigen and CpG oligodeoxynucleotides suppresses tumor growth

BACKGROUND: Prostate-specific membrane antigen (PSMA) is a well characterized prostate-specific tumor associated antigen. Its expression is elevated in prostate carcinoma, particularly in metastatic and recurrent lesions. These observations suggest that PSMA can be used as immune target to induce tu...

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Detalhes bibliográficos
Main Authors: Ren, Jiaqiang, Zheng, Li, Chen, Qi, Li, Hua, Zhang, Lin, Zhu, Hongguang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517950/
https://ncbi.nlm.nih.gov/pubmed/15357867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-2-29
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