Preemptive CD20+ B cell depletion attenuates cardiac allograft vasculopathy in CD154-treated monkeys

BACKGROUND: Anti-CD154 monotherapy is associated with anti-donor alloantibody (Ab) elaboration, cardiac allograft vasculopathy (CAV), and allograft failure in preclinical primate cell and organ transplant models. In the context of calcineurin inhibition (CNI), these pathogenic phenomena are delayed...

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Bibliografiset tiedot
Julkaisussa:Transplantation
Päätekijät: Azimzadeh, Agnes M., Zhang, Tianshu, Wu, Guosheng, Kelishadi, Shahrooz S., Stoddard, Tiffany, O’Neill, Natalie, Nguyen, Bao-Ngoc, Welty, Emily, Avon, Christopher, Higuchi, Mitch, Mitchell, Stuart L., Hershfeld, Alena, Cheng, XiangFei, Kronfli, Anthony, Rybak, Elana, Burdorf, Lars, Pierson, Richard N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179283/
https://ncbi.nlm.nih.gov/pubmed/27362307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001258
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