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Development of docetaxel nanocrystals surface modified with transferrin for tumor targeting

The purpose of this study was to develop the surface modification of docetaxel nanocrystals (DTX-NCs) with apo-Transferrin human (Tf) for improving the cellular uptake and cytotoxicity of DTX. DTX-NCs were prepared by a nanoprecipitation method, and the surface modified with Tf by an adsorption meth...

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Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autori principali: Choi, Jin-Seok, Park, Jeong-Sook
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179213/
https://ncbi.nlm.nih.gov/pubmed/28031702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S122984
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