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Development of docetaxel nanocrystals surface modified with transferrin for tumor targeting

The purpose of this study was to develop the surface modification of docetaxel nanocrystals (DTX-NCs) with apo-Transferrin human (Tf) for improving the cellular uptake and cytotoxicity of DTX. DTX-NCs were prepared by a nanoprecipitation method, and the surface modified with Tf by an adsorption meth...

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Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Choi, Jin-Seok, Park, Jeong-Sook
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179213/
https://ncbi.nlm.nih.gov/pubmed/28031702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S122984
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