Role of CaMKII and PKA in Early Afterdepolarization of Human Ventricular Myocardium Cell: A Computational Model Study

Early afterdepolarization (EAD) plays an important role in arrhythmogenesis. Many experimental studies have reported that Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and β-adrenergic signaling pathway are two important regulators. In this study, we developed a modified computational model...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Comput Math Methods Med
Autori principali: Dai, Ling, Zang, Yunliang, Zheng, Dingchang, Xia, Ling, Gong, Yinglan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5178856/
https://ncbi.nlm.nih.gov/pubmed/28053652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4576313
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