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9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo.

A new class of compounds, 9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] [(RS)-FPMP] derivatives of purines, is described that has selective activity against a broad spectrum of retroviruses [including human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2)] but not other RNA or DNA viruses. Th...

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Detalhes bibliográficos
Main Authors: Balzarini, J, Holy, A, Jindrich, J, Dvorakova, H, Hao, Z, Snoeck, R, Herdewijn, P, Johns, D G, De Clercq, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51787/
https://ncbi.nlm.nih.gov/pubmed/1711214
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