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Mechanism of Prion Propagation: Amyloid Growth Occurs by Monomer Addition

Abundant nonfibrillar oligomeric intermediates are a common feature of amyloid formation, and these oligomers, rather than the final fibers, have been suggested to be the toxic species in some amyloid diseases. Whether such oligomers are critical intermediates for fiber assembly or form in an altern...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Collins, Sean R, Douglass, Adam, Vale, Ronald D, Weissman, Jonathan S
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC517824/
https://ncbi.nlm.nih.gov/pubmed/15383837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0020321
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