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Linking genomic reorganization to tumor initiation via the giant cell cycle
To investigate the mechanisms underlying our recent paradoxical finding that mitotically incapacitated and genomically unstable polyploid giant cancer cells (PGCCs) are capable of tumor initiation, we labeled ovarian cancer cells with α-tubulin fused to green fluorescent protein, histone-2B fused to...
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Publicado no: | Oncogenesis |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5177773/ https://ncbi.nlm.nih.gov/pubmed/27991913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.75 |
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