Immunometabolic Pathways in BCG-Induced Trained Immunity

The protective effects of the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on unrelated infections are thought to be mediated by long-term metabolic changes and chromatin remodeling through histone modifications in innate immune cells such as monocytes, a process termed trained immunity. Here...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Arts, Rob J.W., Carvalho, Agostinho, La Rocca, Claudia, Palma, Carla, Rodrigues, Fernando, Silvestre, Ricardo, Kleinnijenhuis, Johanneke, Lachmandas, Ekta, Gonçalves, Luís G., Belinha, Ana, Cunha, Cristina, Oosting, Marije, Joosten, Leo A.B., Matarese, Giuseppe, van Crevel, Reinout, Netea, Mihai G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177620/
https://ncbi.nlm.nih.gov/pubmed/27926861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.011
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