Immunometabolic Pathways in BCG-Induced Trained Immunity

The protective effects of the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on unrelated infections are thought to be mediated by long-term metabolic changes and chromatin remodeling through histone modifications in innate immune cells such as monocytes, a process termed trained immunity. Here...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Arts, Rob J.W., Carvalho, Agostinho, La Rocca, Claudia, Palma, Carla, Rodrigues, Fernando, Silvestre, Ricardo, Kleinnijenhuis, Johanneke, Lachmandas, Ekta, Gonçalves, Luís G., Belinha, Ana, Cunha, Cristina, Oosting, Marije, Joosten, Leo A.B., Matarese, Giuseppe, van Crevel, Reinout, Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177620/
https://ncbi.nlm.nih.gov/pubmed/27926861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.011
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