BCG-induced trained immunity in NK cells: role for non-specific protection to infection

Adaptive features of innate immunity, also termed ‘trained immunity’, have recently been shown to characterize monocytes of BCG vaccinated healthy volunteers. Trained immunity leads to increased cytokine production in response to non-related pathogens via epigenetic reprogramming of monocytes. Recen...

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Vydáno v:Clin Immunol
Hlavní autoři: Kleinnijenhuis, Johanneke, Quintin, Jessica, Preijers, Frank, Joosten, Leo A.B., Jacobs, Cor, Xavier, Ramnik J., van der Meer, Jos W.M., van Crevel, Reinout, Netea, Mihai G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084088/
https://ncbi.nlm.nih.gov/pubmed/25451159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.10.005
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