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BCG-induced trained immunity in NK cells: role for non-specific protection to infection

Adaptive features of innate immunity, also termed ‘trained immunity’, have recently been shown to characterize monocytes of BCG vaccinated healthy volunteers. Trained immunity leads to increased cytokine production in response to non-related pathogens via epigenetic reprogramming of monocytes. Recen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Immunol
Prif Awduron: Kleinnijenhuis, Johanneke, Quintin, Jessica, Preijers, Frank, Joosten, Leo A.B., Jacobs, Cor, Xavier, Ramnik J., van der Meer, Jos W.M., van Crevel, Reinout, Netea, Mihai G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084088/
https://ncbi.nlm.nih.gov/pubmed/25451159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.10.005
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