Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern

BACKGROUND: The frequency rates of mutations such as KRAS, NRAS, BRAF, and PIK3CA in colorectal cancer (CRC) differ among populations. The aim of this study was to assess mutation frequencies in the Arab population and determine their correlations with certain clinicopathological features. METHODS:...

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Bibliographic Details
Published in:J Gastrointest Oncol
Main Authors: Al-Shamsi, Humaid O., Jones, Jeremy, Fahmawi, Yazan, Dahbour, Ibrahim, Tabash, Aziz, Abdel-Wahab, Reham, Abousamra, Ahmed O. S., Shaw, Kenna R., Xiao, Lianchun, Hassan, Manal M., Kipp, Benjamin R., Kopetz, Scott, Soliman, Amr S., McWilliams, Robert R., Wolff, Robert A.
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177568/
https://ncbi.nlm.nih.gov/pubmed/28078112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2016.11.02
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